Prof Dr. Cesar Mateo | Innovative Leadership | Best Researcher Award
consejo superior de investigaciones científicas | Spain
Author Profile
Education
Dr. Mateo’s academic background integrates strong foundations in biomolecular science, chemistry, and polymeric material applications, although specific institutional affiliations are not listed. His education has evidently been rigorous and interdisciplinary, equipping him with the tools necessary to traverse complex scientific domains. His training emphasized applied enzymology, synthetic chemistry, and biochemical engineering, which underpinned his ability to pioneer new methods in enzyme stabilization and immobilization.
Experience
Throughout his career, César Mateo has directed innovative projects in three key scientific areas: materials chemistry, biomacromolecular chemistry, and polymeric functionalization. At ICP-CSIC, he spearheads a dynamic group focusing on enzyme-catalyzed chemical transformations. His professional trajectory includes extensive experience in both independent and collaborative research, having partnered with over 30 institutions globally, including McGill University (Canada), TU-Delft (Netherlands), and Aix-Marseille University (France). Mateo has also contributed significantly to public science engagement and institutional evaluation panels, participating in international scientific assessment for agencies such as CONACYT (Mexico) and the Czech Science Foundation (GAČR). He has actively supported early-career researchers by supervising doctoral, master’s, and undergraduate theses and providing mentorship in multi-disciplinary environments.
Research Interests
César Mateo’s research is centered on the engineering of heterogeneous biocatalysts with enhanced functionality and stability. His investigations merge the chemistry of biomacromolecules like enzymes, antibodies, and DNA probes with synthetic polymers and functionalized materials. Key focus areas include enzyme immobilization, tailor-made support design, post-immobilization modification, and the development of biosensor technologies. His methodologies enable precise control of molecular interactions, leading to highly stable and recyclable catalytic systems for pharmaceutical, environmental, and industrial applications. Mateo’s innovations also extend to activated supports for large-scale protein purification, with a focus on sustainability and scalability in green chemistry.
Awards
Dr. Mateo has received four official research evaluation periods (sexenios), a significant merit in the Spanish research system that reflects consistent excellence and productivity over long-term periods. In addition to these recognitions, he ranks among the top 2% most-cited researchers in the Spanish National Research Council (CSIC), confirming the profound impact of his scientific contributions. His technologies have led to 14 patents, some of which have been successfully licensed, indicating strong translational value and industrial relevance. His dedication to excellence has earned him a place of esteem among both national and international scientific communities.
Notable Publications
Removal of raffinose and stachyose from soy-based beverages using soluble and immobilized MelA α-D-galactosidase from Lactiplantibacillus plantarum WCFS1
Authors: Alves dos Santos, Leandro; Delgado-Fernández, Paloma; Muñoz-Labrador, Ana; Martin-Gutierrez, Diego; Romero, Evelyn C.; Cuaran, Franzory; Garcia-Alvarez, Andrea; García-Calvo, Elena; de las Rivas, Blanca; Muñoz, Rosario et al.
Journal: Lebensmittel-Wissenschaft und-Technologie – Food Science and Technology
Year: 2024
Enzymatic Glycosylation Strategies in the Production of Bioactive Compounds
Authors: Alicia Andreu; Marija Ćorović; Carla Garcia-Sanz; A. Sofia Santos; Ana Milivojević; Clara Ortega-Nieto; Cesar Mateo; Dejan Bezbradica; Jose M. Palomo
Journal: Catalysts
Year: 2023
Glicosil hidrolasas de Lactiplantibacillus plantarum WCFS1
Authors: Plaza-Vinuesa L.; Hernández-Hernández O.; Sánchez-Arroyo A.; Delgado-Fernández P.; Ferreira-Lazarte A.; Cumella J.; López de Felipe F.; Mancheño JM.; Mateo C.; Palomo JM. et al.
Journal: 15ª Reunión de la Red Española de Bacterias Lácticas (Conference Paper)
Year: 2022
Production and Digestibility Studies of β-Galactosyl Xylitol Derivatives Using Heterogeneous Catalysts of LacA β-Galactosidase from Lactobacillus Plantarum WCFS1
Authors: Eduardo Rosado; Paloma Delgado-Fernández; Blanca de las Rivas; Rosario Muñoz; Francisco Javier Moreno; Nieves Corzo; Cesar Mateo
Journal: Molecules
Year: 2022
Combining phenolic grafting and laccase-catalyzed cross-linking: Effects on structures, technofunctional properties and human immunoglobulin E binding capacity of egg white proteins
Authors: Li, Mingqin; Karboune, Salwa; Liu, Lan; Light, Kelly; L’Hocine, Lamia; Achouri, Allaoua; Pitre, Mélanie; Mateo, Cesar
Journal: Food Chemistry
Year: 2021