Dr. Hojun Kim | Translational research | Best Researcher Award | 3220

Dr. Hojun Kim | Translational research | Best Researcher Award

Korea Institute of Science and Technology, South Korea 

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Early Academic Pursuits 🎓

Hojun Kim’s academic journey began at the prestigious Korea Advanced Institute of Science and Technology (KAIST), where he earned a Bachelor of Science in Materials Science and Engineering in January 2012. His undergraduate performance was nothing short of exceptional, graduating with a GPA of 4.02/4.3 and achieving Summa Cum Laude honors. During his time at KAIST, Kim’s curiosity and drive for research earned him recognition early on, winning the Grand Prize from The Korean Sensors Society in 2010. His stellar academic record was complemented by several scholarships, such as the Samsung Science Talented Person Scholarship (2008-2009) and the Undergraduate Research Program Scholarship (2010), solidifying his foundation in scientific research and innovation.

Kim pursued a Ph.D. in Materials Science and Engineering at the University of Illinois at Urbana-Champaign (UIUC), where he focused on lipid self-assembly for biomedical applications. His dissertation, titled “Structural Study of Lipid Bicontinuous Cubic Phases for Cellular Delivery,” examined the intricate behavior of lipid systems, which has significant implications in the field of drug delivery and gene therapy. Graduating in December 2017 with a perfect GPA of 4.0/4.0, Kim’s early research demonstrated his ability to tackle complex scientific problems with precision and creativity.

Professional Endeavors and Research Contributions 🧑‍🔬

After completing his Ph.D., Kim embarked on a postdoctoral fellowship at UIUC under the mentorship of Professor Cecilia Leal from October 2017 to May 2018. During this period, he made important strides in the phase design of lipid self-assembly for biomedical applications. His postdoctoral work focused on lipid membrane structures that could potentially revolutionize fields like drug delivery and gene therapy.

Following his postdoctoral work, Kim returned to South Korea to continue his scientific career at the Korea Institute of Science and Technology (KIST). He joined as a Research Scientist in June 2018 and was later promoted to Senior Researcher in November 2020. At KIST, Kim specialized in lipid membrane engineering for applications in biosensing and gene therapy. His innovative work on biological vesicles for disease monitoring and mRNA carrier systems has contributed significantly to the ongoing advancements in personalized medicine and nanotechnology.

His research interests are diverse yet interconnected, focusing on topics such as vesicle transport in the extracellular matrix, the origin of super-swelling in lipid lyotropic single crystals, and the development of onsite colloidal biosensors for infectious disease screening. These areas are at the cutting edge of nanomedicine and diagnostic technologies, addressing real-world healthcare challenges with groundbreaking solutions.

Accolades and Recognition 🏆

Throughout his academic and professional career, Kim has earned a plethora of awards and recognitions. Notably, he was honored with the PSK-Innox Young Investigator Award in 2022, reflecting his outstanding contributions to materials science and biomedical research. His accolades also include the Excellent Post-Doc Award at KIST in 2018, which underscored his exceptional research achievements during his early tenure.

During his time at UIUC, Kim was the recipient of the Racheff-Intel Award for Outstanding Graduate Research in 2017 and the MATSE Travel Award in 2014. These awards further validated his potential as a leading scientist in materials science, particularly in the realm of lipid-based technologies for healthcare applications. His work has been frequently highlighted by BRIC (Biological Research Information Center), where he was recognized multiple times as a Notable Korean Scientist (in October 2015, November 2015, September 2017, February 2019, December 2020, and December 2021).

Impact and Influence 🌍

Kim’s research has had a tangible impact on both academia and industry. His contributions to biosensor technologies and nanoparticle platforms have paved the way for non-invasive cancer screening methods, as evidenced by his publication on colloidal lipid-based biosensors for prostate cancer screening. His innovations in the field of mRNA vaccines were particularly relevant during the COVID-19 pandemic, where his work on a lipid nanoparticle platform incorporating trehalose glycolipid contributed to improved safety and efficacy of mRNA-based vaccines.

Kim’s research outputs include several high-impact publications in top-tier journals such as Nano Letters, ACS Nano, Advanced Materials Interfaces, and Proceedings of the National Academy of Sciences. His research on SARS-CoV-2 variant screening using biosensors has been instrumental in advancing diagnostic technologies for viral infections, showcasing his ability to respond to pressing global health challenges with innovative solutions.

Legacy and Future Contributions 🌱

As Hojun Kim continues to advance his research at KIST, his work promises to leave a lasting legacy in the fields of biosensing, gene therapy, and nanomedicine. His commitment to developing cutting-edge technologies that enhance disease monitoring and drug delivery systems positions him as a thought leader in the interdisciplinary space between materials science and biomedical engineering.

Looking ahead, Kim’s future contributions are expected to further blur the boundaries between scientific disciplines, driving innovation in healthcare technologies. His expertise in lipid membrane systems, combined with his passion for solving real-world problems, ensures that his impact will continue to grow, shaping the future of medical diagnostics and personalized treatments.

Kim’s influence extends beyond the laboratory, as he continues to mentor and collaborate with younger researchers, fostering a new generation of scientists committed to tackling some of the world’s most challenging health issues. With an eye on both fundamental research and practical applications, Kim’s work will undoubtedly continue to inspire and influence the next wave of biomedical innovations.

Notable Publications 

High-resolution patterns of quantum dots formed by electrohydrodynamic jet printing for light-emitting diodes

Authors: BH Kim, MS Onses, JB Lim, S Nam, N Oh, H Kim, KJ Yu, JW Lee, JH Kim, et al.

Journal: Nano Letters

Year: 2015

Cuboplexes: Topologically active siRNA delivery

Authors: H Kim, C Leal

Journal: ACS Nano

Year: 2015

Wirelessly controlled, bioresorbable drug delivery device with active valves that exploit electrochemically triggered crevice corrosion

Authors: J Koo, SB Kim, YS Choi, Z Xie, AJ Bandodkar, J Khalifeh, Y Yan, H Kim, et al.

Journal: Science Advances

Year: 2020

Biological lipid membranes for on-demand, wireless drug delivery from thin, bioresorbable electronic implants

Authors: CH Lee*, H Kim*, DV Harburg*, G Park, Y Ma, T Pan, JS Kim, NY Lee, et al.

Journal: NPG Asia Materials

Year: 2015

Microfluidics synthesis of gene silencing cubosomes

Authors: H Kim, J Sung, Y Chang, A Alfeche, C Leal

Journal: ACS Nano

Year: 2018