Assoc Prof Dr. khalid Khan | Organic Chemistry | Best Researcher Award

Assoc Prof Dr. khalid Khan | Organic Chemistry | Best Researcher Award

Islamia College University, Peshawar, Pakistan

Profile 

Orcid

Early Academic Pursuits 🎓

The academic journey of this accomplished chemistry professional began with a Bachelor of Science (BSc) degree in Biological Sciences, Chemistry, Zoology, and Botany from Government College Peshawar (2000-2002). This laid the foundation for a more focused engagement in organic chemistry during a Master of Science (MSc) at the University of Peshawar (2002-2004), where the individual distinguished themselves as a top performer in the class. This early period was marked by a passion for the intricacies of chemical science, ultimately guiding them towards advanced studies.

In 2008, the pursuit of academic excellence took them to Huazhong University of Science and Technology in China, where they embarked on a Ph.D. in Chemistry. The focus of their doctoral research was on the design, synthesis, and loading potential of a new family of nonionic amphiphilic Dendro-Calix[4]arene, under the supervision of Dr. Yan-Song Zhong. During this period, they not only demonstrated technical prowess in synthesis and characterization techniques such as NMR, IR, and HR MS but also acquired deep expertise in examining nanoparticles using methods like Transmission Electron Microscopy (TEM) and Dynamic Light Scattering (DLS). Their dissertation work significantly contributed to the field of nanomaterials and advanced drug delivery systems.

Professional Endeavors and Contributions 🧪

The professional trajectory of this individual at Islamia College University, Peshawar, reflects over 15 years of dedication to teaching, research, and mentoring. They first took on the role of Lecturer (2005-2008) before advancing to Assistant Professor (2013-2020) and later Associate Professor (2020-present) in the Department of Chemistry.

Throughout this period, their research remained focused on cutting-edge topics in chemistry, particularly in synthetic organic chemistry, nanomaterials, and medicinal chemistry. Their work involved supervising numerous graduate and undergraduate research projects, many of which explored structure-activity relationships (SAR) for drug discovery. A notable project involved the design of new derivatives of the antiviral drug Favipiravir for inhibiting the SARS-CoV-II virus, tested using in silico models alongside advanced computational methods like ADDMET, DFT, and MD simulations. This work highlights their versatility in both experimental and computational chemistry, a skill set that has enabled them to collaborate with various national and international research organizations.

In addition to academic mentorship, this professional has contributed significantly to the academic community at Islamia College University through administrative roles, such as being a Warden of two student hostels and serving on several university committees. They have reviewed and examined multiple Ph.D., MPhil, and BS theses, adding to their already robust academic profile.

Research Focus 🔬

A significant portion of this professor’s research revolves around the development and synthesis of complex organic molecules and nanomaterials. Their Ph.D. work on nonionic amphiphilic Dendro-Calix[4]arenes has implications for drug delivery systems, a topic that remains at the forefront of pharmaceutical research today.

Moreover, their ongoing research has made substantial contributions to the understanding of antiviral drug design, particularly against viral infections such as COVID-19. By synthesizing and testing new derivatives of favipiravir, the researcher explored the interaction of these compounds with viral RNA-dependent RNA polymerase, one of the critical proteins in viral replication. Their work blends both theoretical modeling and practical synthesis, emphasizing the synthesis of compounds that not only inhibit viral replication but also show desirable absorption, distribution, metabolism, and toxicity profiles.

Their research contributions extend beyond organic chemistry into the realm of nanotechnology, where their understanding of nanoparticle behavior, size determination, and drug-loading capacity is crucial. The use of advanced techniques such as TEM and DLS in characterizing these particles showcases their expertise in materials chemistry, particularly in developing nanoscale drug delivery systems.

Accolades and Recognition 🏅

The career of this chemist has been marked by a series of awards and accolades that reflect their excellence at every stage of their academic and professional life. They were awarded the Pakistan and Chinese Government Cultural Exchange Scholarship to pursue their Ph.D. in China, a testament to their academic promise and potential.

In addition, they have consistently achieved recognition for their teaching and research. From being a topper during their Master’s degree to securing grants and collaborations with international organizations, they have built a reputation for academic rigor and innovative research. Membership in prestigious organizations like the American Chemical Society and the Royal Chemical Society further attests to their standing in the global scientific community.

Impact and Influence 🌍

Their influence on both students and the broader academic community is profound. Having supervised and mentored numerous Ph.D., MPhil, and BS students, this individual has nurtured the next generation of chemists. Their administrative roles, such as being part of the Tenure Track System Affairs Committee and the Grievances/Conflicts Resolution and Redressal Committee, demonstrate their commitment to improving academic governance.

Furthermore, their research on antiviral drug design has direct implications for global health, particularly in the context of the COVID-19 pandemic. Their work on favipiravir derivatives represents a meaningful contribution to the fight against viral diseases, highlighting the real-world impact of their research.

Legacy and Future Contributions 🌟

Looking forward, this chemist’s future contributions are poised to build upon their extensive background in organic synthesis, nanotechnology, and medicinal chemistry. With ongoing collaborations and an established track record in cutting-edge research, they are well-positioned to make further contributions to antiviral drug development and nanomaterials science. Their leadership in academic mentoring ensures that their legacy will not only be in their own research but also in the students and professionals they have trained, who will continue to advance the frontiers of chemistry.

📝Notable Publications

Metabolic and pharmacological profiling of Penicillium claviforme by a combination of experimental and bioinformatic approaches

Authors: Khalid Khan

Journal: Annals of Medicine

Year: 2022-12-31

Insights into metabolic and pharmacological profiling of Aspergillus ficuum through bioinformatics and experimental techniques

Authors: Khalid Khan

Journal: BMC Microbiology

Year: 2022-12-09

Molecular docking and dynamic simulations of Cefixime, Etoposide, and Nebrodenside A against the pathogenic proteins of SARS-CoV-2

Authors: Khalid Khan

Journal: Journal of Molecular Structure

Year: 2022-01

Structural insights into the Zika virus NS1 protein inhibition using a computational approach

Authors: Khalid Khan

Journal: Journal of Biomolecular Structure and Dynamics

Year: 2021-05-24

Antifungal activity of compounds isolated from Aspergillus niger and their molecular docking studies with tomatinase

Authors: Khalid Khan

Journal: Natural Product Research

Year: 2020-09-16