Dr. Mahdieh Shokrollahi Barough | Team Building and Team Management | Best Researcher Award
Iran University of Medical Sciences, Iran
Profile
🎓 Early Academic Pursuits
Mahdieh Shokrollahi Barough’s journey in medical science began with a remarkable academic record, setting a solid foundation for her later achievements. Driven by a passion for immunology and a keen interest in the molecular mechanisms of cancer, she demonstrated an exceptional commitment to her studies early on. Her dedication was nationally recognized in 2019 when she achieved third place in the highly competitive Ph.D. entrance exam for Medical Immunology. This prestigious ranking marked her as one of the brightest minds in her field, earning her distinguished talent status from the Ministry of Health in Iran. Her academic accomplishments not only underscored her dedication but also positioned her as a promising figure in medical research.
🏥 Professional Endeavors
Mahdieh’s professional journey spans nearly a decade of intensive work in leading research institutions, balancing academic study with hands-on laboratory experience. She spent two formative years at the Iranian Agricultural and Agri-biotechnology Research Institute (IAARI) within Tehran University of Medical Sciences, where she honed her skills in advanced immunological research techniques. Concurrently, she dedicated over seven years to the Motamed Cancer Institute, a premier research center specializing in cancer research. At Motamed, Mahdieh was involved in groundbreaking work in immuno-oncology, an emerging field focused on harnessing the immune system to combat cancer. This experience allowed her to build a bridge between basic research and clinical applications, establishing herself as an innovative thinker who consistently brings academic insights into real-world contexts.
🔬 Contributions and Research Focus
Mahdieh’s research interests lie at the intersection of basic and clinical sciences, with a primary focus on cancer immunotherapy. Her work has yielded significant contributions to the field, particularly in immune-cell therapies. She has spearheaded two pivotal clinical trials examining the therapeutic potential of immune cells in treating cancer. These trials were designed to explore novel methods of reprogramming immune cells to recognize and attack malignant cells, opening new avenues for effective cancer treatments. Her innovative approach also extends to biomaterials, specifically the development of injectable hydrogels for localized cancer therapy. By encapsulating therapeutic agents within these hydrogels, Mahdieh aims to create a controlled release system that targets cancerous tissues directly, minimizing systemic side effects. This groundbreaking work has already shown promising preclinical results, leading to publication in a top-tier medical journal, and positioning her as a forward-thinking researcher in cancer treatment strategies.
🏆 Accolades and Recognition
Mahdieh’s work has not gone unnoticed. Her distinguished ranking in the Ph.D. entrance examination earned her recognition as a notable talent, a title supported by the Ministry of Health in Iran. This recognition came with opportunities for research funding and collaborative projects, enabling her to pursue her innovative ideas in cancer immunotherapy with greater resources. Additionally, her achievements have been celebrated in the academic community, where her contributions to clinical cancer research have positioned her as a rising star. Her published work on injectable hydrogels has garnered attention from her peers, showcasing her as an innovator who continually seeks to translate scientific knowledge into therapeutic solutions. These accolades reflect her impact in her field and underscore her potential to influence future cancer therapies.
🌐 Impact and Influence
Mahdieh’s work in cancer immunotherapy and biomaterial applications has the potential to make a lasting impact on how cancer is treated. Her research on immune-cell therapies contributes to a growing body of knowledge that seeks to treat cancer through less invasive, immune-based methods, moving away from traditional treatments such as chemotherapy and radiation. By focusing on immune-cell therapies, she is at the forefront of a paradigm shift in oncology, one that emphasizes the body’s natural defenses as a weapon against malignancy. Additionally, her work on injectable hydrogels represents a novel approach to targeted cancer therapy, potentially improving patient outcomes by delivering therapeutic agents directly to tumor sites. These contributions highlight her influence as both a scientist and an advocate for innovative cancer treatments, inspiring other researchers to explore interdisciplinary approaches that combine immunology, materials science, and clinical applications.
💫 Legacy and Future Contributions
Looking ahead, Mahdieh Shokrollahi Barough is poised to make lasting contributions to the field of cancer research. Her work bridges critical gaps between basic research, clinical applications, and patient care, with the potential to revolutionize treatment options available to cancer patients. By continuing to pursue innovative approaches to immunotherapy and biomaterials, she aims to establish new, effective modalities that are less toxic and more tailored to individual patient needs. Mahdieh’s commitment to advancing cancer therapies speaks to a vision that extends beyond individual accolades; she seeks to leave a legacy of improved patient care and transformative scientific breakthroughs. As she advances in her career, she remains dedicated to fostering collaborative networks, sharing her knowledge, and inspiring the next generation of scientists who are equally committed to finding sustainable solutions to complex health challenges.
In sum, Mahdieh Shokrollahi Barough’s academic and professional journey is marked by passion, innovation, and a relentless pursuit of excellence in medical science. Her work promises to shape the future of cancer therapy and stands as a testament to her dedication to advancing human health.
📝Notable Publications
Status of peripheral blood natural killer cells and cytotoxicity in women with recurrent pregnancy loss and unexplained infertility
Authors: Parviz Kokhaei, Azam Azargoon, Mahdieh Shokrollahi Barough, Mahdi Barati
Journal: International Journal of Fertility and Sterility
Year: 2019
Necroptosis Triggered by ROS Accumulation and Ca2+ Overload, Partly Explains the Inflammatory Responses and Anti-Cancer Effects Associated With 1Hz, 100 mT ELF-MF in vivo
Authors: M. Barati, M.A. Javidi, B. Darvishi, S.P. Shariatpanahi, Z.S.M. Moosavi, Mahdieh Shokrollahi Barough
Journal: Free Radical Biology and Medicine
Year: 2021
ILP-2 modeling and virtual screening of an FDA-approved library: a possible anticancer therapy
Authors: S. Khalili, H. Mohammadpour, M.S. Barough, P. Kokhaei
Journal: Turkish Journal of Medical Sciences
Year: 2016
Nano‑immunotherapy: overcoming delivery challenge of immune checkpoint therapy
Authors: M.S. Seyed Hossein Kiaie, Hossein Salehi‑Shadkami, Mohammad Javad Sanaei, Mahdieh Shokrollahi Barough
Journal: Nanobiotechnology
Year: 2023
Emerging Advances of Nanotechnology in Drug and Vaccine Delivery against Viral Associated Respiratory Infectious Diseases (VARID)
Authors: M.A. Amir Seyfoori, Mahdieh Shokrollahi Barough, Pooneh Mokarram, Mazaher
Journal: International Journal of Molecular Sciences
Year: 2021