Assoc Prof Dr. khalid Khan | Organic Chemistry | Best Researcher Award

Assoc Prof Dr. khalid Khan | Organic Chemistry | Best Researcher Award

Islamia College University, Peshawar, Pakistan

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Early Academic Pursuits 🎓

The academic journey of this accomplished chemistry professional began with a Bachelor of Science (BSc) degree in Biological Sciences, Chemistry, Zoology, and Botany from Government College Peshawar (2000-2002). This laid the foundation for a more focused engagement in organic chemistry during a Master of Science (MSc) at the University of Peshawar (2002-2004), where the individual distinguished themselves as a top performer in the class. This early period was marked by a passion for the intricacies of chemical science, ultimately guiding them towards advanced studies.

In 2008, the pursuit of academic excellence took them to Huazhong University of Science and Technology in China, where they embarked on a Ph.D. in Chemistry. The focus of their doctoral research was on the design, synthesis, and loading potential of a new family of nonionic amphiphilic Dendro-Calix[4]arene, under the supervision of Dr. Yan-Song Zhong. During this period, they not only demonstrated technical prowess in synthesis and characterization techniques such as NMR, IR, and HR MS but also acquired deep expertise in examining nanoparticles using methods like Transmission Electron Microscopy (TEM) and Dynamic Light Scattering (DLS). Their dissertation work significantly contributed to the field of nanomaterials and advanced drug delivery systems.

Professional Endeavors and Contributions 🧪

The professional trajectory of this individual at Islamia College University, Peshawar, reflects over 15 years of dedication to teaching, research, and mentoring. They first took on the role of Lecturer (2005-2008) before advancing to Assistant Professor (2013-2020) and later Associate Professor (2020-present) in the Department of Chemistry.

Throughout this period, their research remained focused on cutting-edge topics in chemistry, particularly in synthetic organic chemistry, nanomaterials, and medicinal chemistry. Their work involved supervising numerous graduate and undergraduate research projects, many of which explored structure-activity relationships (SAR) for drug discovery. A notable project involved the design of new derivatives of the antiviral drug Favipiravir for inhibiting the SARS-CoV-II virus, tested using in silico models alongside advanced computational methods like ADDMET, DFT, and MD simulations. This work highlights their versatility in both experimental and computational chemistry, a skill set that has enabled them to collaborate with various national and international research organizations.

In addition to academic mentorship, this professional has contributed significantly to the academic community at Islamia College University through administrative roles, such as being a Warden of two student hostels and serving on several university committees. They have reviewed and examined multiple Ph.D., MPhil, and BS theses, adding to their already robust academic profile.

Research Focus 🔬

A significant portion of this professor’s research revolves around the development and synthesis of complex organic molecules and nanomaterials. Their Ph.D. work on nonionic amphiphilic Dendro-Calix[4]arenes has implications for drug delivery systems, a topic that remains at the forefront of pharmaceutical research today.

Moreover, their ongoing research has made substantial contributions to the understanding of antiviral drug design, particularly against viral infections such as COVID-19. By synthesizing and testing new derivatives of favipiravir, the researcher explored the interaction of these compounds with viral RNA-dependent RNA polymerase, one of the critical proteins in viral replication. Their work blends both theoretical modeling and practical synthesis, emphasizing the synthesis of compounds that not only inhibit viral replication but also show desirable absorption, distribution, metabolism, and toxicity profiles.

Their research contributions extend beyond organic chemistry into the realm of nanotechnology, where their understanding of nanoparticle behavior, size determination, and drug-loading capacity is crucial. The use of advanced techniques such as TEM and DLS in characterizing these particles showcases their expertise in materials chemistry, particularly in developing nanoscale drug delivery systems.

Accolades and Recognition 🏅

The career of this chemist has been marked by a series of awards and accolades that reflect their excellence at every stage of their academic and professional life. They were awarded the Pakistan and Chinese Government Cultural Exchange Scholarship to pursue their Ph.D. in China, a testament to their academic promise and potential.

In addition, they have consistently achieved recognition for their teaching and research. From being a topper during their Master’s degree to securing grants and collaborations with international organizations, they have built a reputation for academic rigor and innovative research. Membership in prestigious organizations like the American Chemical Society and the Royal Chemical Society further attests to their standing in the global scientific community.

Impact and Influence 🌍

Their influence on both students and the broader academic community is profound. Having supervised and mentored numerous Ph.D., MPhil, and BS students, this individual has nurtured the next generation of chemists. Their administrative roles, such as being part of the Tenure Track System Affairs Committee and the Grievances/Conflicts Resolution and Redressal Committee, demonstrate their commitment to improving academic governance.

Furthermore, their research on antiviral drug design has direct implications for global health, particularly in the context of the COVID-19 pandemic. Their work on favipiravir derivatives represents a meaningful contribution to the fight against viral diseases, highlighting the real-world impact of their research.

Legacy and Future Contributions 🌟

Looking forward, this chemist’s future contributions are poised to build upon their extensive background in organic synthesis, nanotechnology, and medicinal chemistry. With ongoing collaborations and an established track record in cutting-edge research, they are well-positioned to make further contributions to antiviral drug development and nanomaterials science. Their leadership in academic mentoring ensures that their legacy will not only be in their own research but also in the students and professionals they have trained, who will continue to advance the frontiers of chemistry.

📝Notable Publications

Metabolic and pharmacological profiling of Penicillium claviforme by a combination of experimental and bioinformatic approaches

Authors: Khalid Khan

Journal: Annals of Medicine

Year: 2022-12-31

Insights into metabolic and pharmacological profiling of Aspergillus ficuum through bioinformatics and experimental techniques

Authors: Khalid Khan

Journal: BMC Microbiology

Year: 2022-12-09

Molecular docking and dynamic simulations of Cefixime, Etoposide, and Nebrodenside A against the pathogenic proteins of SARS-CoV-2

Authors: Khalid Khan

Journal: Journal of Molecular Structure

Year: 2022-01

Structural insights into the Zika virus NS1 protein inhibition using a computational approach

Authors: Khalid Khan

Journal: Journal of Biomolecular Structure and Dynamics

Year: 2021-05-24

Antifungal activity of compounds isolated from Aspergillus niger and their molecular docking studies with tomatinase

Authors: Khalid Khan

Journal: Natural Product Research

Year: 2020-09-16

Dr. John Wasswa | Environmental Chemistry | Best Researcher Award

Dr. John Wasswa | Environmental Chemistry | Best Researcher Award

Makerere University, Uganda 

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🎓 Early Academic Pursuits

John Wasswa, born on July 2, 1970, in the Luwero District of Uganda, embarked on an academic journey that would see him become one of Uganda’s leading chemists. His academic foundation was laid at Makerere University, where he pursued a Bachelor of Science degree in Chemistry, graduating with an Upper Second Division in 1994. Driven by a passion for chemistry, Wasswa continued his studies at Makerere, earning a Master of Science degree in Chemistry in 1999. His relentless pursuit of knowledge culminated in a Ph.D. in Chemistry, awarded by Makerere University in 2010. These academic achievements provided him with a solid foundation in chemistry, paving the way for a career marked by scholarly excellence and groundbreaking research.

👨‍🏫 Professional Endeavors

Wasswa’s professional journey spans over two decades, during which he has served in various academic and leadership roles. His career began as a Research Assistant at the Department of Chemistry, Makerere University, from 1995 to 1998. His commitment to teaching and research soon earned him a position as a Lecturer at Mbarara University of Science and Technology, where he also served as the Head of the Department of Chemistry from 1998 to 1999. After returning to Makerere University in 1999, Wasswa steadily rose through the academic ranks, becoming a Senior Lecturer in 2012 and later the Head of the Department of Chemistry from 2016 to 2024. His dedication to education extended beyond Uganda, as he also served as a Visiting Lecturer at Gulu University in 2006 and as a Doctoral Research Fellow at the University of Florida in 2005. Throughout his career, Wasswa has been a mentor to countless students, guiding them in their academic pursuits and inspiring the next generation of chemists.

🔬 Contributions and Research Focus

Wasswa’s research has significantly contributed to the field of environmental chemistry, with a particular focus on the fate and transport of organic pollutants in the environment. His work on legacy and emerging chemicals, including Persistent Organic Pollutants (POPs) and petrochemicals, has had a profound impact on environmental management practices in Uganda and beyond. He has also played a pivotal role in various national and international projects, serving as the Principal Investigator for several internationally funded projects. His expertise in chemicals management has been recognized by his appointments to national steering committees for the Stockholm Convention on POPs, the Sustainable Consumption and Production Plans for Uganda, and the MINAMATA Convention on Mercury Initial Assessment in Uganda.

In addition to his environmental research, Wasswa has made significant contributions to the development of sustainable chemical processes. He has trained in environmental impact assessment, cleaner production technology, and the development of biofuels and bio-based chemicals from agricultural waste. His work in this area has focused on creating environmentally friendly and economically viable solutions to some of the world’s most pressing environmental challenges.

🏆 Accolades and Recognition

Wasswa’s scholarly work has earned him recognition in the scientific community, both in Uganda and internationally. He is a respected reviewer for several highly reputable scientific journals, where his expertise is sought after in the evaluation of research papers. His own research has been widely published in leading journals, including Bioactive Materials, Acta Biomaterialia, ACS Applied Materials & Interfaces, and Chemosphere. These publications are a testament to the quality and impact of his research, particularly in the areas of environmental chemistry and sustainable chemical processes.

🌍 Impact and Influence

Wasswa’s impact extends beyond academia and research. As a Coordinating Lead Expert for the Inventory on E-waste Management Practices in Uganda and Air Quality Standards, he has played a crucial role in shaping environmental policy and standards in Uganda. His work has influenced the management of chemical pollutants, the development of air quality standards, and the implementation of sustainable waste management practices in Uganda. Through his involvement in national and international committees, Wasswa has contributed to the global effort to address environmental challenges and promote sustainable development.

🔮 Legacy and Future Contributions

As John Wasswa continues to build on his impressive career, his legacy is one of dedication to scientific research, education, and environmental stewardship. His work has not only advanced the field of environmental chemistry but has also had a lasting impact on environmental policy and practice in Uganda. Looking to the future, Wasswa is poised to continue his contributions to the scientific community, with a focus on developing sustainable solutions to global environmental challenges. His commitment to mentoring the next generation of chemists ensures that his influence will be felt for years to come, as his students and colleagues carry forward the knowledge and principles he has imparted.

Wasswa’s career serves as an inspiring example of how dedication to research and education can lead to meaningful contributions to society and the environment. His work stands as a testament to the power of science to effect positive change, and his legacy will undoubtedly inspire future generations of scientists to follow in his footsteps.

Notable Publications 

Occurrence, distribution, and ecotoxicological risk assessment of selected pharmaceutical compounds in water from Lake Victoria, Uganda

Authors: Florence Nantaba, John Wasswa, Henrik Kylin, Wolf-Ulrich Palm, Hindrik Bouwman, Klaus Kümmerer

Journal: Chemosphere

Year: 2020

Agricultural expansion as risk to endangered wildlife: Pesticide exposure in wild chimpanzees and baboons displaying facial dysplasia

Authors: Sabrina Krief, Pierre Berny, Fredrick Gumisiriza, Richard Gross, Barbara Demeneix, Jean-Baptiste Fini, et al.

Journal: Science of the Total Environment

Year: 2017

Organochlorine pesticide residues in sediments from the Uganda side of Lake Victoria

Authors: John Wasswa, BT Kiremire, Peter Nkedi-Kizza, James Mbabazi, Paul Ssebugere

Journal: Chemosphere

Year: 2011

Organochlorine pesticides in soils from south-western Uganda

Authors: Paul Ssebugere, John Wasswa, James Mbabazi, SA Nyanzi, BT Kiremire, JAM Marco

Journal: Chemosphere

Year: 2010

Temporal dynamics and ecotoxicological risk assessment of personal care products, phthalate ester plasticizers, and organophosphorus flame retardants in water from Lake Victoria, Uganda

Authors: Florence Nantaba, Wolf-Ulrich Palm, John Wasswa, Hindrik Bouwman, Henrik Kylin, Klaus Kuemmerer

Journal: Chemosphere

Year: 2021