Prof. Dr. Xiaofeng Dai | Authentic Leadership | Best Researcher Award

Prof. Dr. Xiaofeng Dai | Authentic Leadership | Best Researcher Award

Xi’an Jiaotong University Medical College First Affiliated Hospital: The First Affiliated Hospital of Xi’an Jiaotong University, China

Author Profile

Scopus

Early Academic Pursuits 🎓

Dai Xiaofeng’s academic journey exemplifies a commitment to interdisciplinary research and innovation. His early studies took him to Tampere University of Technology, Finland, where he pursued a master’s degree in bioinformatics, and the Chinese Academy of Agricultural Sciences, where he earned a master’s degree in molecular biology. These foundational studies provided him with a solid background in computational and biological sciences, setting the stage for his later achievements. He further advanced his expertise by obtaining a Ph.D. in computational systems biology from Tampere University of Technology, focusing on genome-wide association studies (GWAS) and molecular mechanisms. Not content with a singular academic trajectory, he pursued a second Ph.D. in econometrics from Aalto University, Finland, where he applied computational biological methods to economic modeling. His doctoral education in genetics at the University of Helsinki added yet another layer to his multidisciplinary expertise.

Professional Endeavors and Research Focus 🔬

Following his extensive academic training, Dai Xiaofeng embarked on a research career that took him to the Finnish Center for Molecular Medicine and Helsinki Central Hospital, where he conducted postdoctoral research in GWAS and anti-cancer molecular mechanisms. These experiences allowed him to refine his expertise in genetic research and translational medicine. Upon his return to China, he established a pioneering research group at Xi’an Jiaotong University’s First Affiliated Hospital, focusing on the medical applications of Cold Atmospheric Pressure Plasma (CAP). His work in this domain has led to significant advancements in precision and translational medicine. He has investigated the multimodal anti-cancer molecular mechanisms of CAP and proposed a CAP redox balance model. His research also extends to the development of multi-dimensional anti-cancer tools, including the establishment of the first CAP database both domestically and internationally. He has played a crucial role in developing high-throughput, minimally invasive, and portable CAP medical devices, ensuring that these technologies can be effectively translated from research to real-world medical applications. His efforts to overcome technological barriers in CAP active preservation have further cemented his reputation as a leader in the field.

Contributions and Publications 📚

Dai Xiaofeng’s contributions to scientific literature are substantial. He has authored 104 SCI-indexed papers as the first and/or corresponding author, with his work appearing in top-tier journals such as Signal Transduction and Targeted Therapy, Redox Biology, Progress in Polymer Science, Biotechnology Advances, Advanced Science, Free Radical Biology and Medicine, Computational Biology and Medicine, Trends in Biotechnology, and Trends in Genetics. His research, spanning over 110 internationally published articles, has amassed a total impact factor of 746, highlighting the significance of his findings in both medical and engineering disciplines.

Accolades and Recognition 🏆

Dai Xiaofeng’s innovative research has earned him numerous accolades. His groundbreaking work in CAP translational medicine has been recognized through prestigious research grants and awards, both in China and internationally. His expertise has led to invitations to speak at global conferences on plasma medicine, molecular biology, and biomedical engineering. In addition to his academic honors, his collaborations with leading medical institutions and engineering firms have further reinforced the importance of his research. His contributions to national healthcare policies, particularly through his work on CAP-based therapeutic applications, demonstrate his influence beyond academia.

Impact and Influence 🌟

Dai Xiaofeng’s interdisciplinary research has had a profound impact on multiple fields. His work in CAP-based cancer treatment has introduced non-invasive therapeutic modalities, offering new hope to patients. His contributions to medical device innovation have led to the development of cutting-edge plasma-based tools, which are poised to revolutionize the treatment landscape. His emphasis on translational medicine ensures that groundbreaking research is not confined to laboratories but reaches the clinical setting, where it can benefit real patients. Beyond his own research, he has dedicated himself to mentoring young scientists, fostering a new generation of researchers capable of bridging multiple scientific disciplines.

Legacy and Future Contributions 🌐

Dai Xiaofeng’s legacy is one of innovation, interdisciplinary collaboration, and a relentless pursuit of scientific advancement. Looking ahead, he aims to expand CAP-based therapeutics into broader clinical applications, ensuring that these technologies become a staple in modern medical treatment. His future work will focus on the integration of artificial intelligence into CAP devices, optimizing their therapeutic potential. Strengthening collaborations between academia, industry, and healthcare providers remains a priority, as does advocating for policy changes that support the integration of CAP technology into mainstream medical practice. Through his pioneering research, Dai Xiaofeng continues to shape the future of biomedical science, leaving an indelible mark on the fields of medicine, engineering, and computational biology.

📝Notable Publications
  • Spermidine antagonizes the anti-cancer effect of cold atmospheric plasma and induces transit G0/G1 cell cycle arrest of triple negative breast cancers
    Authors: L. Shen, X. Lv, Y. Li, X. Dai
    Journal: Free Radical Biology and Medicine
    Year: 2025

  • Cold atmospheric plasma potentiates ferroptosis via EGFR(Y1068)-mediated dual axes on GPX4 among triple negative breast cancer cells
    Authors: X. Dai, Z. Xu, X. Lv, M. Xi, T. Li
    Journal: International Journal of Biological Sciences
    Year: 2025

  • Cold atmospheric plasma restores skewed macrophage polarization in triple negative breast cancers via enhancing KAT6A acetylation
    Authors: K. Zhu, Q. Lv, X. Lu, Y. Wang, X. Dai
    Journal: Free Radical Biology and Medicine
    Year: 2025

  • Metal-organic frameworks: potential synergies with cold atmospheric plasmas for cancer control
    Authors: X. Dai, Y. Yang
    Journal: Journal of Materials Chemistry B
    Year: 2024

  • Magnetic nanoparticles and possible synergies with cold atmospheric plasma for cancer treatment
    Authors: X. Dai, Y. Dai, Y. Zheng, Y. Lv
    Journal: RSC Advances
    Year: 2024

Dr. Jiongjiong Fan |Authentic Leadership | Best Researcher Award

Dr. Jiongjiong Fan |Authentic Leadership | Best Researcher Award

China National Rice Research Institute, China

Profile

Scopus

Early Academic Pursuits 🎓

Dr. Jiongjiong Fan’s academic journey began with a strong foundation in bioengineering at the Henan Institute of Science and Technology, where he earned his Bachelor of Science (B.Sc.) degree in 2016. With a deep interest in the biological sciences and a passion for agricultural biotechnology, he advanced his studies in Biochemistry and Molecular Biology at Shanghai Normal University. Under the mentorship of Professor Zhu Jun, he pursued his Master of Science (M.Sc.) degree from 2016 to 2018. His research during this period focused on molecular mechanisms underlying plant growth and stress responses, laying the groundwork for his future contributions to agricultural science.

Driven by his commitment to addressing environmental challenges in agriculture, Dr. Fan furthered his expertise in Environmental Engineering at Shanghai Normal University. Guided by Professor Huang Xuehui, he earned his Doctor of Philosophy (Ph.D.) degree in 2022. His doctoral research explored innovative approaches to sustainable agriculture, emphasizing environmental protection and resource efficiency. This period of rigorous academic training equipped him with interdisciplinary skills, bridging the gap between environmental science and agricultural biotechnology.

Professional Endeavors and Research Contributions 🌿

Upon completing his Ph.D., Dr. Fan embarked on a postdoctoral journey at the China National Rice Research Institute (CNRRI) in June 2022. As part of the National Southern Rice Variety Testing and Evaluation Laboratory, he collaborates with esteemed advisors Yang Shihua and Gong Junyi. His research primarily revolves around the genetic improvement and environmental adaptability of rice varieties, with a particular focus on stress resistance, yield enhancement, and sustainability in rice production.

Dr. Fan has been instrumental in pioneering innovative techniques for evaluating and improving rice cultivars. His work integrates molecular biology, genetic engineering, and environmental sciences to develop rice varieties that can withstand climate change-induced stresses such as drought, salinity, and pest infestations. Through cutting-edge genomic research and precision breeding techniques, he aims to enhance the resilience of rice crops, ensuring food security for millions.

Accolades and Recognition 🏆

Dr. Fan’s exceptional contributions to agricultural biotechnology have earned him numerous accolades and recognitions. His groundbreaking research has been published in prestigious scientific journals, contributing significantly to the field of rice genetics and environmental sustainability. He has also been invited to present his findings at national and international conferences, where he shares his expertise with fellow researchers and policymakers.

His work has not only gained recognition in academia but has also attracted attention from agricultural industries and governmental bodies seeking sustainable solutions for rice production. Through his dedication and expertise, Dr. Fan has become a respected figure in the field, influencing the next generation of agricultural scientists.

Impact and Influence 💡

Dr. Fan’s research has far-reaching implications beyond academia. By developing climate-resilient rice varieties, he contributes to global food security and sustainable agriculture. His innovative methodologies in rice breeding and environmental adaptation strategies are being adopted by research institutions and agricultural industries worldwide.

His mentorship of young scientists and collaboration with fellow researchers further amplify his influence. By fostering interdisciplinary research, he bridges the gap between theoretical knowledge and practical agricultural applications, ensuring that his scientific contributions translate into real-world benefits for farmers and consumers alike.

Legacy and Future Contributions 🌱

As Dr. Fan continues his journey at the China National Rice Research Institute, his vision remains clear: to revolutionize rice production through sustainable and innovative research. He aims to expand his research on stress-resistant rice varieties, exploring novel genetic modification techniques to enhance crop performance under challenging environmental conditions.

In the coming years, he plans to deepen his collaboration with global agricultural organizations, contributing to international efforts in combating food scarcity and climate change. His legacy will be defined by his unwavering dedication to agricultural sustainability, environmental conservation, and scientific innovation.

Dr. Jiongjiong Fan’s journey exemplifies the power of research and innovation in addressing some of the most pressing challenges in agriculture. His work not only strengthens the scientific community but also leaves a lasting impact on the global food system, ensuring a more sustainable and resilient future for generations to come.

📝Notable Publication

Genomic investigation of 18,421 lines reveals the genetic architecture of rice”

Authors: Wei, X., Chen, M., Zhang, Q., Han, B., Huang, X.

Journal: Science (New York, N.Y.)

Year: 2024

“Phenotypic evolution of appearance quality and cooking and taste quality of hybrid rice over the past 40 years in China”

Authors: Fan, J., Li, W., Bian, Y., Zhang, X., Gong, J.

Journal: Frontiers in Plant Science

Year: 2024

“Natural variation of ZmLNG1 alters organ shapes in maize”

Authors: Wang, Q., Fan, J., Cong, J., Liu, H., Huang, X.

Journal: New Phytologist

Year: 2023

“Whole-Genome Sequencing of 117 Chromosome Segment Substitution Lines for Genetic Analyses of Complex Traits in Rice”

Authors: Fan, J., Hua, H., Luo, Z., Huang, X., Wang, Q.

Journal: Rice

Year: 2021

“OsMS188 Is a Key Regulator of Tapetum Development and Sporopollenin Synthesis in Rice”

Authors: Han, Y., Zhou, S.-D., Fan, J.-J., Zhu, J., Yang, Z.-N.

Journal: Rice

Year: 2021