Department of Anatomy, Faculty of Medicine | Iran
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Early Academic Pursuits
Dr. Fatemeh Tahmasebi began her academic journey with a strong focus on the medical sciences, specializing in the intricate field of human anatomy. Her academic pursuits were rooted in deep scientific curiosity, which laid the foundation for her future as a research-driven academic. Her doctoral studies concentrated on anatomical sciences, a discipline that demands both rigorous theoretical knowledge and exceptional laboratory proficiency. These formative years were critical in shaping her understanding of the complexities of the human nervous system, cellular interactions, and regenerative medicine—areas that would later become central to her research identity.
Professional Endeavors
Currently serving as an Assistant Professor at the School of Medicine, Mashhad University of Medical Sciences, Dr. Tahmasebi has established herself as a dedicated academic and researcher. In her role as a faculty member, she not only contributes to the education of medical students but also actively mentors research scholars in highly technical, experimental studies. Her professional career has been consistently aligned with high-impact areas in neuroanatomy and tissue engineering, with particular focus on spinal cord injuries, neurodegeneration, and neural regeneration. She has demonstrated exceptional leadership in numerous research projects, often taking on the role of executive investigator, managing all aspects of experimental design, implementation, and data analysis.
Contributions and Research Focus
Dr. Tahmasebi’s research portfolio is both extensive and multidisciplinary, merging neurobiology, stem cell therapy, nanotechnology, and regenerative medicine. She has made significant strides in developing innovative approaches to treating spinal cord injuries and neurodegenerative diseases using adipose-derived mesenchymal stem cells, nanofiber scaffolds, and targeted drug delivery systems. Her research projects include studies on the phenotypic modulation of glial cells, the interaction of neurons and astrocytes in disease models, and the use of nanotechnology to enhance the efficacy of regenerative treatments.
One of her hallmark contributions is the use of polymeric and carbon nanotube-based scaffolds enriched with therapeutic agents like curcumin, hesperidin, and ellagic acid to enhance recovery in spinal cord injury models. Additionally, she has led groundbreaking investigations into the role of microRNAs in neural degeneration, especially in Parkinson’s disease and multiple sclerosis models. Her pioneering work on the use of exosome-loaded hydrogels for targeted drug delivery exemplifies her dedication to translational research that bridges the gap between basic science and clinical application.
Dr. Tahmasebi’s research also extends to developmental neuroscience. She has explored how maternal diabetes impacts the expression of neurotransmitter receptors in neonates, offering insights into developmental neurobiology and the intergenerational effects of metabolic disorders.
Accolades and Recognition
Her scientific achievements are reflected in her prolific publication record in peer-reviewed, high-impact journals indexed in ISI, Scopus, PubMed, and other international databases. Many of her articles have been published in reputed journals such as the Journal of Cellular Physiology, Neuropeptides, Journal of Molecular Histology, Journal of Cellular Biochemistry, Cell Journal, and Journal of Chemical Neuroanatomy. In these works, she often appears as the first or corresponding author, demonstrating her leadership in research conceptualization and execution.
Beyond publications, Dr. Tahmasebi has also collaborated on several major research projects, bringing together expertise across multiple institutions and research centers. Her role as a co-investigator in numerous studies reflects her capacity to contribute both technically and intellectually to multidisciplinary scientific efforts.
Impact and Influence
Dr. Tahmasebi’s work has had a meaningful impact on both academic scholarship and biomedical research related to neuroregeneration. Her focus on integrating stem cell biology with nanomedicine to treat conditions like multiple sclerosis and spinal cord injuries addresses urgent global health challenges. Her research on microglial and astrocyte modulation has helped deepen understanding of the cellular microenvironment during neurodegeneration and repair. By advancing therapies that utilize bioengineered scaffolds and exosomes, she is actively shaping the future of neural tissue engineering and personalized regenerative medicine.
Furthermore, her contributions have inspired a new generation of researchers, particularly in Iran, to pursue high-level, applied biomedical research. Through her involvement in postgraduate mentorship and interdisciplinary collaborations, she is helping to build research capacity and elevate the scientific standards in anatomical and neurological sciences.
Legacy and Future Contributions
Dr. Fatemeh Tahmasebi’s academic legacy is one of innovation, collaboration, and commitment to societal health. Her work stands at the crossroads of anatomical science, regenerative medicine, and nanotechnology. As research in neural repair and neuroplasticity continues to evolve, she is well-positioned to lead new initiatives in translational neuroscience. Her future endeavors are likely to include the development of bioresponsive scaffolds, gene regulation therapies via miRNAs, and deeper investigations into neuroimmune interactions during injury recovery.
She is poised to further influence medical science not only through pioneering research but also through active engagement in scientific dissemination and community health education. Her continued presence in academia and research will undoubtedly contribute to a deeper understanding of complex neurobiological processes and the development of more effective therapeutic strategies.
Notable Publications
Effect of the CSF1R inhibitor PLX3397 on remyelination of corpus callosum in a cuprizone‐induced demyelination mouse model
Authors: F. Tahmasebi, P. Pasbakhsh, K. Mortezaee, S. Madadi, S. Barati, I.R. Kashani
Journal: Journal of Cellular Biochemistry
Year: 2019
Masitinib: The promising actor in the next season of the Amyotrophic Lateral Sclerosis treatment series
Authors: A.H.M.E. Ketabforoush, R. Chegini, S. Barati, F. Tahmasebi, B. Moghisseh, …
Journal: Biomedicine & Pharmacotherapy
Year: 2023
Mesenchymal stem cell mediated effects on microglial phenotype in cuprizone‐induced demyelination model
Authors: S. Barati, I. Ragerdi Kashani, F. Moradi, F. Tahmasebi, S. Mehrabi, M. Barati, …
Journal: Journal of Cellular Biochemistry
Year: 2019
Astrocyte ablation induced by La-aminoadipate (L-AAA) potentiates remyelination in a cuprizone demyelinating mouse model
Authors: S. Madadi, P. Pasbakhsh, F. Tahmasebi, K. Mortezaee, M. Khanehzad, …
Journal: Metabolic Brain Disease
Year: 2019
The effect of microglial ablation and mesenchymal stem cell transplantation on a cuprizone‐induced demyelination model
Authors: F. Tahmasebi, P. Pasbakhsh, S. Barati, S. Madadi, I.R. Kashani
Journal: Journal of Cellular Physiology
Year: 2021